5-CHLORO-2-METHOXYPHENYL ISOCYANATE

5-CHLORO-2-METHOXYPHENYL ISOCYANATE - Names and Identifiers

Name	5-Chloro-2-methoxyphenyl isocyanate
Synonyms	5-Chloro-2-methoxyphenyl isocyanate 5-CHLORO-2-METHOXYPHENYL ISOCYANATE 2-METHOXY-5-CHLORO PHENYL ISOCYANATE 4-chloro-2-isocyanato-1-methoxybenzene Benzene, 4-chloro-2-isocyanato-1-methoxy-
CAS	55440-54-5
InChI	InChI=1/C8H6ClNO2/c1-12-8-3-2-6(9)4-7(8)10-5-11/h2-4H,1H3

5-CHLORO-2-METHOXYPHENYL ISOCYANATE - Physico-chemical Properties

Molecular Formula	C8H6ClNO2
Molar Mass	183.59
Density	1.22g/cm³
Melting Point	58-61°C(lit.)
Boling Point	271.7°C at 760 mmHg
Flash Point	118.1°C
Vapor Presure	0.00633mmHg at 25°C
BRN	2719682
Storage Condition	Room Temprature
Sensitive	Moisture Sensitive/Lachrymatory
Refractive Index	1.534
MDL	MFCD00013860

5-CHLORO-2-METHOXYPHENYL ISOCYANATE - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	2206
WGK Germany	3
Hazard Note	Toxic/Corrosive/Lachrymatory/Moisture Sensitive
Hazard Class	6.1
Packing Group	III

5-CHLORO-2-METHOXYPHENYL ISOCYANATE - Introduction

5-Chloro-2-methoxyphenyl isocyanate is an organic compound with the chemical formula C8H6ClNO2.

Its main properties are as follows:
1. appearance: colorless to yellowish liquid.
2. Molecular weight: 183.59g/mol.
3. Boiling point: 210-212°C.
4. Melting point:-5°C.
5. Solubility: Soluble in organic solvents such as ethanol, dimethyl sulfoxide, etc.
6. stability: sensitive to sunlight, heat and moisture, should be stored in a dry, cool place.

Application of 5-Chloro-2-methoxyphenyl isocyanate:
1. used as raw materials and intermediates in organic synthesis.
2. It may play an important role in the field of drug synthesis, such as the synthesis of pesticides and pharmaceutical active parts.
3. can be used for dye synthesis and functionalization of polymer materials.

Preparation Method:
5-Chloro-2-methoxyphenyl isocyanate can be prepared by reacting 4-chloro-2-methoxyaniline with phosgene. Specific steps are as follows:
1. Dissolve 4-chloro-2-methoxyaniline in an organic solvent.
2. Add excess phosphorus trichloride, and filter to remove impurities after the reaction.
3. reacting the reaction product with phosgene to generate 5-Chloro-2-methoxyphenyl isocyanate.

Safety Information:
1. 5-Chloro-2-methoxyphenyl isocyanate is irritating and should avoid skin contact and inhalation.
2. use should wear protective gloves and respiratory system protective equipment.
3. Waste disposal shall comply with local regulations and shall not be discharged into water or soil.

Last Update：2024-04-09 02:00:46